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546 Although less sensitive, biomarkers like creatine, creatine kinase, free carnitine, and acylcarnitine in the blood can aid in diagnosing mitochondrial diseases caused by fatty acid -oxidation disorders

Genetic predisposition testing may help provide context about individual variation in peptide pathways, but it does not predict exact medication response

These CAFs uptake OxLDL and activate the PPARG-FABP4 axis, leading to ANGPTL4 secretion that promotes CD8+ T cell exhaustion

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