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It says that at 72 weeks participants on all three doses of the experimental drug showed clinically meaningful weight loss when accompanied by a healthy diet and physical activity compared to the placebo group

Immunotherapy and Combination Approaches Although MPNST is generally considered an immune-cold tumor, 2025 trials are combining PD-1 blockade with MEK inhibitors or radiation therapy to enhance immune activation

It plays a critical role in protecting the body against oxidative stress, detoxifying harmful substances, supporting immune function, and maintaining overall cellular health

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