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Despite the identification of N-acetyl cysteine, a reactive oxygen species scavenger that is regarded as an effective clinical treatment, therapeutic effectiveness remains limited due to rapid disease progression and diagnosis at a late phase, which leads to the need to explore various therapeutic approaches

10.1016/s0928-4257(99)00119-9 112 SikiricP.MikusD.SeiwerthS.GrabarevicZ.RucmanR.PetekM.et al (1997b)

72 The effect of long-term administration of high doses of GSH on cells or organ systems remains unclear

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