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Bruton's tyrosine kinase inhibitors: a new generation of promising agents for multiple sclerosis therapy
Swelling in your hands, feet, or ankles that is new
The buffer you drew earlier is what gets pushed out here
Medical Evaluation Investigate potential medical contributors to weight loss resistance: Thyroid function: Check TSH if not recently assessed, as hypothyroidism impairs weight loss Medications: Review for weight-promoting drugs (antipsychotics, certain antidepressants, corticosteroids) Sleep disorders: Screen for sleep apnea and insufficient sleep, both associated with weight loss resistance Stress and cortisol: Chronic stress elevates cortisol, promoting central adiposity and metabolic dysfunction Dose Optimization If patients have not reached the maximum tolerated dose, consider further titration according to FDA labeling
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