drawbacks of glp 1 GLP-1 drugs have a broad impact on patients, providers, the economy A large new study on

liver glucose production decreases22 and intestinal glucose uptake increases, acting as a hyperglycemia clearance mechanism in diabetes.23 The effect of metformin on body weight is neutral, though in some cases it induces modest weight loss.24 While it is a safe drug, its gastrointestinal side effects appear to be underestimated in the literature.4 Gradual dose titration and administration with food is advised in order to improve tolerance of this drug

Afamelanotide (Scenesse): FDA-approved MC1R agonist for erythropoietic protoporphyria

28 The objective of the trial was to compare the addition of oral semaglutide (14 mg once daily) or the sodium-glucose cotransporter-2 (SGLT-2) inhibitor empagliflozin (25 mg once daily) to metformin monotherapy in patients with uncontrolled T2DM

Furthermore, the polymer syringe can be customized to accommodate various viscosities and volumes, making it versatile for different types of medications and devices