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10.1016/0304-3940(81)90259-7 Neurosci

Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified

It is frustrating to us as Patient Advocates that initial evidence relied on was not at that time suitably researched or understood and now, 30 years on, of course, we know so much more