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In type 1 diabetes, where IGF-I and IGFBP-3 levels are decreased[302], substitutive rhIGF-I/IGFBP-3 therapy enhances protein[303] and glucose metabolism by controlling both endogenous glucose output and peripheral glucose uptake[304]

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The Maryland-based biopharma joins Eli Lilly and Novo Nordisk in trialing a GLP-1 agonist for alcohol- and liver-related conditions