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doi: 10.1073/pnas.0701549104 54 ZenattiPPRibeiroDLiWZuurbierLSilvaMCPaganinMet al
This expansion or duplication of genes resulted in sequence variations that expanded substrate functionality and/or responses to environmental stresses [62, 70, 71]
Patients with pernicious anemia have an irreversible cause of deficiency, so its important to ensure other factors do not contribute to further deficiency progression
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