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During the trial, 10% of patients in each of the Wegovy and placebo arms discontinued treatment
This imbalance sustains a self-amplifying loop of oxidative stress, neuroinflammation, and mitochondrial dysfunction, reinforcing chronic pain pathophysiology
Whole grains like oats and brown rice in modest portions, and healthy fats from avocado, nuts, and olive oil, round out balanced meals that keep blood sugar stable and energy steady
Any future treatment would need to suppress damaging inflammation without disabling the immune functions required for protection
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