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Gross Medicare costs were about $42 billion for all of the drugs chosen for negotiation this year
Suresh Kumar, Biomed
Gallup found that the use of these drugs specifically to lose weight (theyre also used to treat diabetes) has more than doubled from February 2024, when it was 5.8%, to 12.4% currently: More women (15.2%) are taking the drugs than men (9.7%), which correlates with a slightly larger decline in obesity rates among women
Metformin is associated with higher relative abundance of mucin-degrading Akkermansia muciniphila and several short-chain fatty acid-producing microbiota in the gut
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