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The goal during the first 12 weeks is establishing sustainable habits rather than maximizing intensity
STEP-8 (N=338) directly compared semaglutide to liraglutide 3.0 mg, showing semaglutide achieved 15.8% weight loss versus 6.4% for liraglutide [11]
The scale matters, but body composition, protein, and strength tell you whether the result will hold
It suggests that the anti-inflammatory properties of GLP-1 medications may be partially mediated through similar microbiome pathways that Pendulum is targeting
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