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Symptoms include pain, swelling, itching, and bleeding

Weight loss continues accelerating, typically reaching 8 to 12 percent of baseline by week 12

Resection surgery is the main therapy for MPNST, while radiation and systemic chemotherapy was also widely used despite their uncertain effect

As noted earlier, nephrologists commonly find the eGFR to be slightly below 60 mL/min/1.73 m 2 in elderly persons with no evidence of kidney disease who have a serum creatinine that is stable at a slightly elevated level

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