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Name: does glp 1 burn fat or muscle GLP1 Loss Do GLP-1 drugs shrink your
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On average, patients who switched from semaglutide to orforglipron regained about 2 pounds of the weight they lost over the course of a year (almost 42 pounds total)

DPP-4i was selected as the active comparator given its documented cardiovascular neutrality, whereas sodium-glucose cotransporter-2 inhibitors were not used as a comparator due to their established cardiovascular benefits