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This severe glutathione deficit was accompanied by elevated ventricular lactate, a clear biomarker indicating that the brains of these patients are relying on highly inefficient, oxygen-deprived anaerobic metabolism due to mitochondrial stress
This allows for smaller injection volumes but requires more precise measurement
The blood circulation of the nanoparticles was assessed upon intravenous injection into the tail vein of healthy female mice and determination of the metal content in the blood by ICP-MS
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