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1) CT 388 has shown a placebo-adjusted WL of 8.5% after 4 weeks in a phase 1 trial [50]
Nausea that persists beyond week four warrants a PlexusDx provider consultation
Semaglutide (brand name Wegovy) was the most commonly prescribed AOM, followed by AOM tirzepatide (brand name Zepbound)
However, a notable side effect was observed: MT-II-treated normal C57BL/6J mice exhibited significant weight loss, with their average weight decreasing from a baseline of 30.9 1.4 grams to 26.5 1.7 grams after the 14-day treatment course, a change not seen in vehicle-treated controls
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