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Conclusion: In non-diabetic cases with CHD, SGLT2 inhibitor therapy significantly reduced heart failure-related events and major cardiovascular events with good safety and tolerability

Extracellular glutathione peroxidase (Gpx3) binds specifically to basement membranes of mouse renal cortex tubule cells

Ex-4 modulates apoptotic pathways in the hippocampus through the regulation of the expression levels of Bcl2, Bax, and caspase-3 [71], and it improves mitochondrial function and integrity in AD mice through the PI3K/Akt signaling pathway [72]

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