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However, the efficacy of nasal absorption may vary among research subjects, and it may not be as potent as the injectable route

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: Hydrocortisone : Glucocorticoid (Corticosteroid) : Replacement therapy in adrenal insufficiency (Addisons disease) Treatment of inflammatory and allergic conditions (asthma, arthritis, dermatitis, anaphylaxis) Management of severe infections with shock (in septic shock with refractory hypotension) Topical use in eczema, rashes, and skin allergies : Hydrocortisone binds to intracellular glucocorticoid receptors alters gene expression decreases production of inflammatory mediators (prostaglandins, cytokines) anti-inflammatory & immunosuppressive effects

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