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Mechanistically, oxidative inactivation of tyrosine phosphatase SHP-2 by HO stimulates the activation of downstream effectors like kinase Syk and phospholipase C2, mobilizing calcium ions and activating protein kinase C, ultimately promoting thrombin/protease-activated receptor responsiveness and platelet aggregation (Stalker et al

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For plasma biochemical profiles analysis, overnight fasting blood samples were obtained and centrifuged at 3000 r.p.m

Temperature matters: Many people find cold or room-temperature foods easier to tolerate than hot foods when nauseous