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The foundational chemistry was reported by Al-Obeidi, Castrucci, Hadley, and Hruby in J Med Chem 1989, describing the design rationale based on molecular dynamics modeling [2]
Sterile water can be used for immediate single-use applications, but bacteriostatic water is required for any multi-dose protocol
Resistance training is strongly recommended to prevent muscle loss, promote fat loss, and help with toning and skin tightening
Pregnancy If you are pregnant or breastfeeding, you may not be suitable for B12 injections, but it is still safe for you and your baby if you take a limited dose of B12 orally
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