Neurosci Lett 658:3236 Keshavarz-Bahaghighat H et al (2018) Acetyl-l-carnitine attenuates arsenic-induced oxidative stress and hippocampal mitochondrial dysfunction
An alternative perspective posits that the gut harbors a substantial population of immune cells and neural networks, and EGCG has the potential to modulate signaling and functional disruptions in intestinal neuroimmune communication via the brain-gut axis (13, 209211)
Conclusion Increasing evidence suggests that anti-diabetes medicine, GLP-1R agonists, have multiple neuroprotective mechanisms in AD models, such as anti-inflammation, anti-oxidative stress, reducing A aggregation/deposition and tau protein hyperphosphorylation, reducing neuronal apoptosis and neurotoxicity, increasing cell proliferation and neurogenesis, increasing synaptic plasticity, and other beneficial effects
New research reveals how GLP-1 receptor drugs, known for treating diabetes and obesity, also protect the brains vital neurovascular system, offering hope for tackling cognitive decline and neurodegenerative diseases like Alzheimer's