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This vagal impairment is a central driver of dysautonomia and Postural Orthostatic Tachycardia Syndrome (POTS), conditions frequently comorbid with Long COVID and ME/CFS
Additionally, M1-type macrophages can secrete pro-inflammatory cytokines such as TNF- and IL-1, which further drive the inflammatory process (289, 292)
amylin receptors in area postrema/NTS) and overlapping but distinct effects on gastric emptying and satiety signaling
Surgery and Anesthesia Risks Because these medications keep your stomach full longer, there is an increased risk of pulmonary aspiration (inhaling stomach contents into your lungs) when you are put under anesthesia for surgery [2] [8]
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