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Mechanistically, (+)-CLA prevents Nrf2 ubiquitination and boosts Nrf2 stability by selectively interacting with the cys-151 residue of Keap1 (Wang et al., 2020)
Using both together gives your skin double the antioxidant protection and a more consistent, faster improvement in tone and radiance than either ingredient could deliver alone
Oxidative stress plays a predominant role in the formation of skin wrinkles
10.1016/j.lfs.2017.08.006 88 StupnisekM.KokotA.DrmicD.Hrelec PatrljM.Zenko SeverA.KolencD.et al (2015)
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