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It is a fair concern

Genetically determined ancestry group based on ADMIXTURE with K = 10 (where K refers to the number of ancestral clusters inferred in the ADMIXTURE analysis), with grouping based on which 1000 Genomes phase 3 reference samples (with superpopulation labels as reference) showed the highest proportion for a given class

PIONEER TEENS looked at three doses of oral semaglutide 3 mg, 7 mg, or 14 mg per day which were given on top of background therapy with metformin, basal insulin, or both drugs to 132 children aged 10 to 17 with T2D