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Patients who experience significant side effects at any dose can remain at that dose longer (6-8 weeks) before escalating, or step back to the previous dose temporarily before attempting escalation again
GIP receptor activation complements the effects of GLP-1, further enhancing satiety and helping the body process and store nutrients more efficiently
Seek urgent medical attention (call 999 or attend A&E) if you experience: Difficulty breathing or swallowing Swelling of the face, lips, tongue, or throat (angioedema) Widespread urticaria accompanied by dizziness, rapid pulse, or feeling faint Severe chest tightness or wheezing Blistering, peeling skin, or mucosal involvement (mouth, eyes, genitals) These symptoms may indicate anaphylaxis or a severe hypersensitivity reaction requiring immediate emergency treatment with adrenaline and supportive care
These same pathways connect to your reproductive hormone system, creating potential cross-talk between weight-loss signaling and estrogen/progesterone balance
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