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The shoulder Experienced doctors commonly administer B12 injections into the upper arm area by inserting the injection into the deltoid (shoulder) muscle
A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes (p=0.270)
Special Populations Post-Bariatric Surgery Patients : Individuals who have undergone bariatric surgery, such as Roux-en-Y gastric bypass, are at a higher risk of vitamin B12 deficiency due to malabsorption
Some more severe, but rare, side effects that can occur are low potassium levels, muscle cramps, irregular heartbeat, chest pains, or blurred vision
