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Li X, Staszewski L, Xu H, Durick K, Zoller M, Adler E
Significant weight loss particularly reduction of visceral fat is associated with improvements in testosterone levels in men with obesity-related hypogonadism, as visceral fat drives conversion of testosterone to oestrogen
An ongoing study is evaluating the pharmacokinetics, safety, and dose optimization, but it is likely to be administered orally once-daily
Compared with traditional small-molecule drugs, GLP-1 peptides are structurally more complex and can exist in multiple molecular forms
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