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JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells
It has been shown that glioma cells overexpressing galectin-1 are capable to evade NK immune surveillance, whereas the lack of galectin-1 leads to accentuated tumor-killing effects of NK cells by releasing granzyme B [50, 77]
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A rare cause of neonatal hemolytic anemia: glutathione synthetase deficiency
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