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We next investigated the NHR-49::YFP 295422 truncation to better understand how impaired ligand binding impacts its subcellular dynamics and transcriptional activity during fasting and refeeding

They both showed that overexpression of ferroptosis suppressor protein 1(FSP1), which was initially named apoptosis-inducing factor mitochondrial 2 (AIFM2), could protect cells from ferroptotic death