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Rare but serious risks include pancreatitis, gallbladder disease, and a thyroid C-cell tumor risk based on rodent studies (semaglutide carries a boxed warning and is contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN2)

Cell 75 , 241251 (1993)

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Each sample was diluted to the appropriate concentration with 1 mM HCl and then injected at 50 L