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Nrf2, a transcription factor, is activated upon oxidative stress signals and binds to the ARE in the promoter regions of target genes, triggering the expression of antioxidative enzymes 83
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Although this treatment may not change the course of acute liver failure or accelerate the recovery, it can prevent reinfection in the transplanted liver if liver transplant becomes indicated
Understanding why fatigue occurs and how to manage it effectively can help patients optimise their treatment experience whilst maintaining therapeutic benefits
