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If you feel sluggish or tired, it might be because your body isnt getting enough B12
Why do B12 shots hurt so much when dissolved in water
The two most common variants of the MTHFR mutation are C677T and A1298C, which can reduce the enzymes function by 30-70%, depending on the combination of gene variants you inherit
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It is possible that compensatory mechanisms could develop that reduce efficacy with prolonged use
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