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Consider incorporating both topical and injectable forms based on patient needs and treatment goals
You should have baseline labs (HbA1c, renal function, lipids) and periodic monitoring every 36 months once stable
Hollander PA et al (2001): Importance of early insulin secretion: comparison of nateglinide and glyburide in previously diet-treated patients with type 2 diabetes
More is better. Over 700 mcg per dose shows diminishing returns and higher injectionsite irritation
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