is sitagliptin a glp 1 Renal dosing for DPP-4 inhibitors Linagliptin: No dose adjustment required at any stage of CKD (exam favorite). Sitagliptin: Dose reduction required as eGFR falls. Saxagliptin: Dose reduction required. Alogliptin: Dose reduction required Hypothesised anti-fibrotic mechanisms activated in
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