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Subsequently, it declined steadily: 4.6 1.88 on day 2 ( P = 0.389), 3.57 2.43 on day 3 ( P = 0.036), 4.14 2.01 on day 4 ( P = 0.127), 4.07 2.21 on day 5 ( P = 0.127), 4.14 1.91 on day 6 ( P = 0.136) and 3.14 1.75 on day 7 ( P = 0.003)

Similar results were reported in the study of Chen et al., where high TMAO levels increased the expression of tumor necrosis factor- (TNF-) and interleukin-6 (IL-6), but inhibited the expression of anti-inflammatory cytokine interleukin-10 (IL-10), thereby accelerating cellular inflammation in obese mice treated with a Western diet (73)

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