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As PD progresses, patients eventually become severely disabled due to loss of motor control, imposing a heavy social burden (25)
Furthermore, a recent clinical study in women with obesity treated with semaglutide showed improved recognition of basic tastes, altered gene expression in the tongue (measured by tongue biopsy), decreased activation of putamen in response to calorie-dense sweet and savory food cues, and increased cortical brain activity in response to the sweet taste stimulus compared to placebo
Duivelshof BL, Murisier A, Camperi J, Fekete S, Beck A, Guillarme D, et al
Combining the low doses with Noom's GLP-1 Companion support app "helps more patients stay on the treatment, experience the full health benefits of these medications, and make real progress in reducing obesity and overweight rates in the US," said the company's chief medical officer, Dr Jeffrey Egler
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