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Increases in blood folate indices are similar in women of childbearing age supplemented with [6S]-5-methyltetrahydrofolate and folic acid

Reported, but not confirmed in a controlled study Important limits Frequency, dose link, and cause are unknown

Side effects Side effects may include: bleeding skin infection at the site of injection increased appetite flushed face menstrual irregularities temporary increase in blood sugar diarrhea nausea More serious complications may include: infection damage to nerves spinal headache weakened muscles increase in pain death of bone tissue, called avascular necrosis a pain disorder called arachnoiditis paralysis Doctors do not use discographies often

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