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In conclusion, hyperglycemia, IR, abnormal insulin secretion from pancreatic -cells, and glucose metabolic disturbances are closely interrelated and interact synergistically to exacerbate disease severity in AP
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Another study reported that the bitter taste of berberine causes the activation of bitter taste receptors (TAS2Rs), which further activates the downstream signalling pathway, leading to enhanced GLP-1 secretion 4
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