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This is standard medical practice same way doctors prescribe medications for uses beyond their original approval all the time
Initial studies used a redox probe, which allowed a measurement of ratios, but not absolute concentrations, and measured redox state throughout the secretory pathway rather than specifically in the ER (Hwang et al , 1992)
Future research comparing cortisol levels before and after GLP-1 initiation, stratified by baseline stress, will clarify whether these medications offer direct stress-hormone benefits independent of weight loss
There are glutathione pills sold in the market as well
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