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Induction of apoptosis by S -nitrosoglutathione and Cu 2+ or Ni 2+ ion through modulation of bax, bad, and bcl-2 proteins in human colon adenocarcinoma cells
It has also been studied for wound healing and angiogenesis through the VEGFR2 pathway
The anti-inflammatory effect is so strong, one study found chicory can give osteoarthritis sufferers dramatic relief
These barriers are physically represented by the so-called tight junctions between brain endothelial cells and epithelial cells, attributed to the special proteins such as occludin, claudins, and the associated proteins zona occludens (ZO-1, ZO-2, and ZO-3), which are highly expressed in brain endothelium (Chen et al., 2009
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