how do semaglutides cause weight loss Semaglutide and Loss: What Experts Say Why GLP-1 drugs like semaglutide

L.LevinD.MohanM.ForteathC.BeallC.et al (2016)

Mechanism of action (MOA): Metformin help to control blood glucose level by reducing hepatic glucose production by activating AMPK enzyme and by increasing insulin sensitivity it increasing glucose uptake in muscle and fat tissue

Possible Side Effects (usually mild and temporary): Soreness or redness at the injection site Mild nausea Headache Temporary digestive changes Serious side effects are rare but can include allergic reactions or vitamin imbalances, particularly with excessive or unsupervised use

By activating GLP-1 receptors, semaglutide stimulates insulin secretion, inhibits glucagon secretion, and slows down gastric emptying