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In this combined analysis, we observe that the degree of BMI loss depends strongly on sex, drug type, time on treatment and drug dosage, consistent with previous reports 11 , and has a relatively weak dependence on pre-treatment BMI (with higher starting BMI associated with greater BMI loss)
Figure 1 presents a flowchart of the study selection process
10.1210/en.2009-0220 Endocrinology 71 WilliamsD
Seventy-two percent ( n =88) of all malignant peripheral nerve sheath tumors demonstrated complete loss of staining with the anti-H3K27me3 monoclonal antibody (Figures 1b,2b, 2c and 3b, 3c, 3e, 3f)
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