Nonetheless, in patients at high risk of sarcopenia, tailored management including nutritional optimization and concurrent resistance training should be considered to mitigate potential adverse consequences during pharmacologically induced weight loss [20]
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NA generated by gut microbes is also able to maintain a local NAD + /NAM pool that can be a source of circulating NA even in the absence of dietary precursor administration 126,127
Efficacy and Safety of Liraglutide and Semaglutide on Weight Loss in People with Obesity or Overweight: A Systematic Review