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Key trials demonstrate: SUSTAIN-1 : HbA1c reduction ~1.45-1.55% with modest weight loss (~3.734.53 kg )
The degree of weight loss achieved with retatrutide is greater than that seen with semaglutide or tirzepatide, which may theoretically increase the risk of nutritionally mediated telogen effluvium
Coskun 2022 mmc3 Table 3 + mmc1 Table S8 Phase 1 single-ascending-dose study (NCT03841630, n=45, conducted in Singapore)
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