I have witnessed people with uncontrolled Hashimotos and overt hypothyroidism who can work an 80 hour week, run a household, become elite body builders, and/or run marathons, while others can barely drag themselves out of bed in the morning and have to go on disability due to debilitating symptoms, even while taking thyroid meds
But now theres another question coming up: does semaglutide cause muscle loss

Seek urgent medical attention if you experience: Severe or persistent abdominal pain, particularly if it radiates to your back this may indicate pancreatitis or gallbladder disease, which have been associated with GLP-1 receptor agonist class medicines [16] [17] Persistent vomiting or an inability to keep fluids down, which may lead to dehydration Yellowing of the skin or eyes, or dark urine (possible signs of liver or gallbladder problems) Signs of a serious allergic reaction, such as facial swelling, difficulty breathing, or a widespread rash Contact your prescriber or trial team if: Hunger is severe, persistent, and significantly interfering with your ability to adhere to the treatment plan You are experiencing rapid or unexpected weight gain despite taking the medication as prescribed You notice symptoms that may suggest hypoglycaemia (low blood sugar), such as shakiness, sweating, confusion, or palpitations

Pharma Industry 1 min read Novo Nordisk and ELi Lilly Likely to maintain clout in GLP-1R market : GlobalData Novo Nordisk and Eli Lilly, the dominant players in the GLP-1R market, are expected to collectively capture 94 per cent of the projected $142 billion GLP-1R sales by 2030