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Methods Number of Prescriptions and Gross Spending Data: This analysis uses 2019 through 2024 State Drug Utilization Data (SDUD) (downloaded in January 2026)
Redox control at the level of methionine biosynthesis Enzymes catalyzing the two first steps of methionine synthesis, i.e., CGS and CBL, are present only in chloroplasts and are encoded by a single gene while MS are encoded by three genes, with two isoforms being expressed in the cytosol (MS1 and MS2) and one in chloroplasts (MS3) (Figure 1
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