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Patients with type 2 diabetes and obesity are typically considered for tirzepatide first given the dual glycemic and weight benefit documented in SURMOUNT-2 [6]

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I dont know whether its purely the patch, or the combination of the patch and my gradual return to exercise but one thing is certain: since I started using it, I feel like Ive got my life back

Control of mitochondrial morphology by SPHKAP-dependent ERMCS-localised GLP-1R signalling As the main role of MIC19 is to orchestrate mitochondrial cristae assembly 45 and enable the transfer of lipid precursors during mitochondrial remodelling 11 , we next assessed whether GLP-1R stimulation would play a role in mitochondrial remodelling processes in INS-1 832/3 cells, and whether this would be affected by SPHKAP knockdown