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Personalized antioxidant support for your well-being As we age, maintaining antioxidant levels becomes crucial
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Importantly, 5FU-based combination treatment also shows an increase in mitochondrial mass (FOLFOX (5FU + 1 M oxaliplatin) or FOLFIRI (5FU + 5 nM SN38, active metabolite of irinotecan)) that we attribute to 5FU-imposed stress, given that single-agent oxaliplatin or SN38 do not promote the same degree of mitochondrial adaptation (Extended Data Fig
TGF- signaling operates through canonical (Smad-dependent) and noncanonical (Smad-independent) pathways
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