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Brain GLP-1/IGF-1 signaling and autophagy mediate exendin-4 protection against apoptosis in type 2 diabetic rats

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Peter Attia, another longevity expert in the field of aging, is particularly optimistic about rapamycins potential to extend life by preventing diseases associated with aging

Potential mechanism: By inhibiting the expression of myostatin, negative regulation of muscle growth can be relieved.Diabetes foot ulcer: local application of IGF-1 LR3 gel (0.1 mg/cm ) can accelerate wound closure, and its mechanisms include:Stimulate fibroblast migration and collagen synthesis.Promote the secretion of vascular endothelial growth factor (VEGF) and improve local blood supply