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performed a cross-trial analysis using data from clinical trials of GLP-1RAs (ELIXA, LEADER, SUSTAIN-6, EXSCEL, HARMONY, REWIND, PIONEER-6 [59], and AMPLITUDE-O), SGLT2is (CANVAS and CREDENCE), and finerenone (FIDELIO-DKD and FIGARO-DKD) to estimate the effects of the triple combination therapy of GLP-1RA, SGLT2i, and finerenone using the actuarial method [60]

The research on this connection remains preliminary, but the anecdotal reports are consistent enough to mention

However, it is still unclear how to protect against these toxic effects

In many cases, therapy sessions that arent tied to a formal mental health diagnosis may not be covered