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These are women, primarily, who have reported back to us that [using GLP-1s] wasnt worth the weight loss. Eli Lillys recent retatrutide clinical trial did not evaluate participants changes in muscle or bone mass, a company spokesperson tells Scientific American

Gastrointestinal losses combined with reduced food and fluid intake can deplete sodium, potassium, magnesium, and chloride, affecting cardiac rhythm, muscle function, and cellular metabolism

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